MidwestSports.Net ranks the top 10 football teams in the midwest region in NCAA Division II and NAIA for Sept. 23, 2018.
DIVISION II
| Ranking | Team | Record | Previous | Last Week / This Week |
| 1 | Southern Arkansas | (4-0) | 2 | Def. Northwestern Okla., 27-14 Sept. 29 at Oklahoma Baptist |
| 2 | Pittsburg State | (4-0) | 3 | Def. Nebraska-Kearney, 30-17 Sept. 29 at Lindenwood |
| 3 | Ouachita | (4-0) | 4 | Def. East Central, 42-0 Sept. 29 vs. Arkansas Tech |
| 4 | Northwest Missouri | (3-1) | 1 | Lost to Central Okla., 31-21 Sept. 29 vs. Emporia State |
| 5 | Fort Hays State | (3-1) | 6 | Def. Missouri Southern, 55-20 Sept. 29 vs. Central Oklahoma |
| 6 | Harding | (3-1) | 7 | Def. Oklahoma Baptist, 56-7 Sept. 29 at Ark.-Monticello |
| 7 | Chadron State | (3-1) | 9 | Def. Colorado Mesa, 38-34 Sept. 29 vs. Western State |
| 8 | Missouri S&T | (3-1) | 10 | Def. Tuskegee, 16-7 Sept. 29 vs. Southwest Baptist |
| 9 | Central Oklahoma | (2-2) | NR | Def. Northwest Missouri Sept. 29 at Fort Hays State |
| 10 | Central Missouri | (2-2) | 5 | Lost to Washburn, 28-21 Sept. 29 vs. Missouri Southern |
NAIA
| Ranking | Team | Record | Previous | Last Week / This Week |
| 1 | Morningside | (4-0) | 1 | Def. Briar Cliff, 56-0 Sept. 29 a Hastings |
| 2 | Northwestern (Iowa) | (4-0) | 2 | Def. Dakota Wesleyan, 41-13 Sept. 29 vs. Doane |
| 3 | Evangel | (5-0) | 3 | Def. Culver-Stockton, 20-17 Sept. 29 at William Penn |
| 4 | Kansas Wesleyan | (4-0) | 5 | Def. Ottawa, 70-24 Sept. 29 at Bethany |
| 5 | Avila | (4-0) | 7 | Def. St. Mary, 67-28 Sept. 29 at Southwestern |
| 6 | Langston | (2-1) | 4 | Def. Bethany, 42-35 Sept. 22 at Kansas Wesleyan |
| 7 | Midland | (3-1) | 9 | Def. Concordia, 35-7 Sept. 29 vs. Jamestown |
| 8 | Benedictine | (3-1) | 10 | Def. MidAmerica Nazarene Sept. 29 at Baker |
| 9 | Grand View | (2-1) | 8 | Idle Sept. 29 at Missouri Valley |
| 10 | Baker | (3-1) | NR | Def. Graceland, 0-14 Sept. 29 vs. Benedictine |